Inhibiting protein biofouling using graphene oxide in droplet-based microfluidic microsystems.
نویسندگان
چکیده
Biofouling or adsorption of biomolecules onto surfaces in microfluidic devices limits the type of samples which can be handled. In this paper, we take advantage of the high adsorption capacity of graphene oxide (GO) for proteins as a strategy to limit biofouling, while preserving their activity for droplet-based lab-on-chip applications.
منابع مشابه
Fluorescent Contrast agent Based on Graphene Quantum Dots Decorated Mesoporous Silica Nanoparticles for Detecting and Sorting Cancer Cells
Background and Objectives: The inability of classic fluorescence-activated cell sorting to single cancer cell sorting is one of the most significant drawbacks of this method. The sorting of cancer cells in microdroplets significantly influences our ability to analyze cancer cell proteins. Material and Methods: We adapted a developed microfluidic device as a 3D in vitro model to sorted MCF-7 c...
متن کاملDroplet-based 3d Graphene Structure Synthesis
In this study, we presented a droplet-based microfluidic system for synthesizing three-dimensional (3D) graphene structure, called graphene popcorn. The droplets that were obtained by varying the flow rates and the concentration of graphene oxide (GO) solution were incubated in the furnace for rapid evaporation, resulting in the reduction of the GO as well as the aggregation of GO to form the g...
متن کاملPreparation and Characterization of an Antifouling Polyethersulfone Nanofiltration Membrane Blended with Graphene Oxide/Ag Nanoparticles
Graphene oxide/Ag nanoparticles (Ag/GO) was prepared and employed to synthesize antifouling polyethersulfone (PES) mixed matrix membranes. The performance of the membranes was evaluated in terms of flux, hydrophilicity and anti-biofouling properties. With increment of the Ag/GO from 0 to 0.1 wt.%, the pure water flux increased from 24.7 up to 54.1 kg/m2 h. The flux recovery ratio (FRR) of the m...
متن کاملNumerical Study of Droplet Generation Process in a Microfluidic Flow Focusing
Microfluidic flow focusing devices have been utilized for droplet generation on account of its superior control over droplet size. Droplet based microfluidics addressed many scientific issues by providing a novel technological platform for applications such as biology, pharmaceutical industry, biomedical studies and drug delivery. This study numerically investigated the droplet generation proce...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Lab on a chip
دوره 12 9 شماره
صفحات -
تاریخ انتشار 2012